Activated Clotting Time (ACT)
The ACT test tubes, made of either glass or plastic, contain various blood coagulation activators. The degree of “contact activation” of the fresh whole blood sample is dependent upon the activator found in the test tube, as well as the test tube material.
 
The choice of which ACT test tube to use depends upon the degree of anticoagulation used in the clinical setting. High heparin levels require a strong activator for accurate monitoring. Lower heparin doses need a moderate ACT activator: Clinical applications for the ACT include: baseline determinations, ECMO, Dialysis, Critical Care, Cath Lab. Non-Cardiac OR, and Cardiac Bypass Surgery.
 
HRFTCA510 (Black top)
Celite® (diatomaceous earth) activated, non-evacuated glass test tube. Features flip-top for needleless blood sample transfer: Requires 2.0cc of fresh whole blood. Barcode allows HEMOCHRON Response instruments to recognise test. Recommended for monitoring heparin during cardiac surgery, vascular surgery, PTCA, cardiac catheterization, extracorporeal circulation, sheath pull, monitoring heparin drips, and post procedure monitoring.
 
HRFTK-ACT (Gold top)
Kaolin activated, non-evacuated glass test tube. Features flip-top for needleless blood sample transfer: Requires 2.0cc of fresh whole blood. Barcode allows HEMOCHRON Response instruments to recognise test. Recommended for monitoring heparin in the presence of low to moderate doses of aprotinin during bypass surgery, and angioplasty.
 
P214 (Clear top)
Glass-particulate activated, non-evacuated plastic test tube. Features flip-top for needleless blood sample transfer: Requires 0.4cc of whole blood. Recommended for monitoring heparin during hemodialysis, hemofiltration, and ECMO.
 
RxDx® Anticoagulation Management System
Every day, medical professionals face the constant challenge of providing safe, effective anticoagulation in cardiac bypass surgery. The RxDx system provides a more standardised and predictable approach to hemostasis management by assuring effective anticoagulation therapy. It offers heparin and protamine monitoring assays both independent and linked to injectable pharmaceuticals. In this way, both drug variability and patient sensitivity are taken into consideration to more accurately predict heparin and protamine doses.
 
The coagulation profile of a cardiac patient may be further complicated by previous exposure to heparin and treatment with thrombolytic agents or nitroglycerin. With the RxDx system, heparin resistant and heparin sensitive patients are dosed according to their individual dose response rather than simply their weight, resulting in lower protamine doses, less post-operative blood loss, and reduced administration of transfusion products.
 
RxDx® Heparin Response Test
For bypass surgery and aggressive cardiac invasive procedures. Contains heparin and either diatomaceous earth (Celite) or kaolin activator. The Celite HRT is used in conjunction with the Celite ACT. The Kaolin HRT is used in conjunction with the kaolin ACT. Celite system is available matched to HEMOCHRON heparin (U.S.ONLY).
Clinical applications for HRT include: determining the bolus heparin dose during cardiac bypass surgery.
 
R-HRT480P (Mint Green top)
Porcine heparin with Celite activator.
 
R-HRT480PK (Mint Green top)
Porcine heparin with Kaolin activator.
 
Protamine Response Test
For bypass surgery when specified levels of heparin are present. Contains protamine and either diatomaceous earth (Celite) or kaolin activator. The Celite PRT is used in conjunction with the Celite ACT. The Kaolin PRT is used in conjunction with the kaolin ACT. Celite system is available matched to HEMOCHRON protamine (U.S.ONLY).
Clinical applications for the PRT include: determining the protamine dose required to reverse the effects of heparin given during cardiac bypass surgery.
 
R-PRT200 (Peach top)
Protamine with Celite activator. For use with low to moderate heparin levels.
 
R-PRT200K (Peach top)
Protamine with kaolin activator. For use with moderate to high heparin levels.
 
R-PRT400 (Red top)
Protamine with Celite activator. For use with low to moderate heparin levels.
 
R-PRT400K (Red top)
Protamine with kaolin activator. For use with moderate to high heparin levels.
 
Protamine Dose Assay (PDAO)
Verifies complete heparin neutralisation following protamine administration at the close of cardiac bypass surgery. Can be used to calculate the subsequent protamine dose required to neutralise any residual heparin. Used in conjunction with a Celite ACT. Contains protamine sulphate and diatomaceous earth.
Clinical applications for the PDAO include: quantifying of additional protamine requirements at the conclusion of cardiac bypass surgery.
 
PDAO (Orange top)
Protamine with Celite activator. For detection of trace amounts of on-board heparin.
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